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Monitoring soluble cMET and ctDNA in metastatic uveal melanoma patients to track early disease progression on immunotherapies

Abstract Background Metastatic uveal melanoma (mUM) is a rare malignancy and is different from metastatic cutaneous melanoma (mCM) in tumor characteristics and efficacy to immunotherapies. Tumor-specific biomarkers are required for mUM patients to monitor early disease progression on immunotherapies...

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Principais autores: Devayani Machiraju, Christian H Ziener, Elena Clementi, Francisco García-Asencio, Jennifer Hüllein, Jasmin Richter, Bénédicte Lenoir, Melanie Wiecken, Daniel Hübschmann, Dirk Jäger, Jessica C Hassel
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-07-01
coleção:Journal of Experimental & Clinical Cancer Research
Assuntos:
Metastatic uveal melanoma
Liver metastasis
Biomarkers
Immune checkpoint inhibitors
Tebentafusp
Liquid biopsy
Acesso em linha:https://doi.org/10.1186/s13046-025-03451-2
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