Integrative multi-omics profiling deciphers tumor microenvironment heterogeneity and immunotherapy vulnerabilities in lung neuroendocrine carcinomas

Introduction: Lung neuroendocrine carcinomas (Lu-NECs) are rare, highly aggressive lung tumors with poor prognosis and limited therapeutic options. Understanding the tumor immune microenvironment (TIME) is crucial towards personalized therapeutic strategies. Objectives: This study aims to systematic...

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Podrobná bibliografie

Hlavní autoři:	Zicheng Zhang, Modi Zhai, Siqi Bao, Xujie Sun, Ruanqi Chen, Bingning Wang, Fan Yang, Lin Yang, Meng Zhou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-03-01
Edice:	Journal of Advanced Research
Témata:	Lung neuroendocrine carcinomas (Lu-NECs) Multi-omics Tumor microenvironment Tumor heterogeneity
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2090123225004278
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