Peripheral immune indicators and their predictive value in disease progression or relapse of pediatric Langerhans cell histiocytosis

Objective: Langerhans cell histiocytosis (LCH) is a rare inflammatory myeloid neoplasm in which the inflammatory microenvironment plays a crucial role in the development and progression of disease. The prognostic value of circulating lymphocyte subsets and cytokines remains uncertain. Methods: The a...

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Main Authors: Hua-Lin Li, Hong-Yun Lian, Wen-Yu Gong, Shuo Tian, Wei-Jing Li, Qing Zhang, Chan-Juan Wang, Hong-Hao Ma, Dong Wang, Yun-Ze Zhao, Zi-Jing Zhao, Jia-Jia Dong, Zhi-Gang Li, Rui Zhang, Lei Cui
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2025-11-01
Series:Jornal de Pediatria
Assuntos:
Lymphocyte subsets
Cytokines
Pediatric langerhans cell histiocytosis
Progression-free survival
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S002175572500155X
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