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Beyond plasmid addiction: the role of toxin–antitoxin systems in the selfish behavior of mobile genetic elements

ABSTRACT Toxin-antitoxin (TA) systems were initially described as “addiction” modules that promote plasmid maintenance through a post-segregational killing (PSK) mechanism. In this process, the cells are forced to retain plasmids to avoid death caused by the longer half-life of the toxin compared to...

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Bibliografiske detaljer
Principais autores: Bradd Mendoza-Guido, Keilor Rojas-Jimenez
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2025-10-01
Serier:Journal of Bacteriology
Fag:
Online adgang:https://journals.asm.org/doi/10.1128/jb.00232-25
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