CD56neg CD16+ cells represent a distinct mature NK cell subset with altered phenotype and are associated with adverse clinical outcome upon expansion in AML

IntroductionAcute myeloid leukemia (AML) is a rare haematological cancer with poor 5-years overall survival (OS) and high relapse rate. Leukemic cells are sensitive to Natural Killer (NK) cell mediated killing. However, NK cells are highly impaired in AML, which promote AML immune escape from NK cel...

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Κύριοι συγγραφείς:	Julia Wlosik, Florence Orlanducci, Manon Richaud, Clemence Demerle, Amira Ben Amara, Marie-Sarah Rouviere, Philippe Livrati, Laurent Gorvel, Marie-Anne Hospital, Nicolas Dulphy, Raynier Devillier, Norbert Vey, Daniel Olive, Anne-Sophie Chretien
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2025-01-01
Σειρά:	Frontiers in Immunology
Θέματα:	CD56 neg NK cells AML high-dimensional cytometry RNA-sequencing cancer
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1487792/full
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