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COX-2-derived prostanoids and oxidative stress additionally reduce endothelium-mediated relaxation in old type 2 diabetic rats.

Endothelial dysfunction in resistance arteries alters end organ perfusion in type 2 diabetes. Superoxides and cyclooxygenase-2 (COX-2) derivatives have been shown separately to alter endothelium-mediated relaxation in aging and diabetes but their role in the alteration of vascular tone in old diabet...

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Bibliografische gegevens
Hoofdauteurs: Emilie Vessières, Anne-Laure Guihot, Bertrand Toutain, Maud Maquigneau, Céline Fassot, Laurent Loufrani, Daniel Henrion
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2013-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC3706542?pdf=render
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