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The PML-nuclear inclusion of human supraoptic neurons: a new compartment with SUMO-1- and ubiquitin–proteasome-associated domains

It is well known that the cell nucleus is organized in structural and functional compartments involved in transcription, RNA processing and protein modifications such as conjugation with SUMO-1 and proteolysis. Promyelocytic leukaemia (PML) bodies are dynamic nuclear structures that concentrate PML...

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Principais autores: Nuria T. Villagra, Joaquin Navascues, Iñigo Casafont, J. Fernando Val-Bernal, Miguel Lafarga, Maria T. Berciano
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2006-01-01
Serier:Neurobiology of Disease
Fag:
PML bodies
Marinesco bodies
Intranuclear rodlets
SUMO-1
Ubiquitin–proteasome system
CREB-binding protein (CBP)
Online adgang:http://www.sciencedirect.com/science/article/pii/S0969996105001993
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