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Thyrotropin-releasing hormone neurons of different hypothalamic nuclei increase energy expenditure

Abstract Several neuronal populations in the hypothalamus and brainstem express thyrotropin-releasing hormone (TRH). While TRH neurons in the paraventricular nucleus (PVN) regulate the thyroid axis, the roles of other TRH-producing neurons remain largely unknown. Here we investigate the role of TRH...

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Hauptverfasser: Andreea Constantinescu, Akila Chandrasekar, Lena Kleindienst, Luca Höhne, Natalia Da Silva Lima, Marius Richter, Vanessa Neve, Frauke Spiecker, Ines Stölting, Wiebke Brandt, Urte Matschl, Jan Wenzel, Rebecca Oelkrug, Vincent Prevot, Heike Heuer, Jens Mittag, Ruben Nogueiras, Markus Schwaninger, Helge Müller-Fielitz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2026-04-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/s41467-026-71617-3
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