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Evaluation of 12 GWAS-drawn SNPs as biomarkers of rheumatoid arthritis response to TNF inhibitors. A potential SNP association with response to etanercept.

Research in rheumatoid arthritis (RA) is increasingly focused on the discovery of biomarkers that could enable personalized treatments. The genetic biomarkers associated with the response to TNF inhibitors (TNFi) are among the most studied. They include 12 SNPs exhibiting promising results in the th...

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Principais autores: Aida Ferreiro-Iglesias, Ariana Montes, Eva Perez-Pampin, Juan D Cañete, Enrique Raya, Cesar Magro-Checa, Yiannis Vasilopoulos, Rafael Caliz, Miguel Angel Ferrer, Beatriz Joven, Patricia Carreira, Alejandro Balsa, Dora Pascual-Salcedo, Francisco J Blanco, Manuel J Moreno-Ramos, Sara Manrique-Arija, María Del Carmen Ordoñez, Juan Jose Alegre-Sancho, Javier Narvaez, Federico Navarro-Sarabia, Virginia Moreira, Lara Valor, Rosa Garcia-Portales, Ana Marquez, Juan J Gomez-Reino, Javier Martin, Antonio Gonzalez
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2019-01-01
coleção:PLoS ONE
Acesso em linha:https://doi.org/10.1371/journal.pone.0213073
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