SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis.

<h4>Background</h4>Human African trypanosomiasis (HAT) is an important public health problem in sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need exists for the discovery and development of new, safe, and effective drugs to treat HAT, as existing therapies suffer fro...

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Detalhes bibliográficos

Principais autores:	Robert T Jacobs, Bakela Nare, Stephen A Wring, Matthew D Orr, Daitao Chen, Jessica M Sligar, Matthew X Jenks, Robert A Noe, Tana S Bowling, Luke T Mercer, Cindy Rewerts, Eric Gaukel, Jennifer Owens, Robin Parham, Ryan Randolph, Beth Beaudet, Cyrus J Bacchi, Nigel Yarlett, Jacob J Plattner, Yvonne Freund, Charles Ding, Tsutomu Akama, Y-K Zhang, Reto Brun, Marcel Kaiser, Ivan Scandale, Robert Don
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2011-06-01
coleção:	PLoS Neglected Tropical Diseases
Acesso em linha:	https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001151&type=printable
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