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A robust and reliable non-invasive test for stress responsivity in mice

Stress and an altered stress response have been associated with many multifactorial diseases, such as psychiatric disorders or neurodegenerative diseases. As currently mouse mutants for each single gene are generated and phenotyped in a large-scale manner, it seems advisable also to test these mutan...

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Principais autores: Annemarie eZimprich, Lillian eGarrett, Jan M Deussing, Carsten T. Wotjak, Helmut eFuchs, Valerie eGailus-Durner, Martin eHrabe de Angelis, Wolfgang eWurst, Sabine M Hölter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014-04-01
coleção:Frontiers in Behavioral Neuroscience
Assuntos:
Corticosterone
open field test
acute restraint stress
mouse mutants
behavioural read-out
hyperlocomotion
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00125/full
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