Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein

Albumin binding domain derived affinity proteins (ADAPTs) are a class of small and folded engineered scaffold proteins that holds great promise for targeting cancer tumors. Here, we have extended the in vivo half-life of an ADAPT, targeting the human epidermal growth factor receptor 2 (HER2) by fusi...

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Principais autores:	Javad Garousi, Haozhong Ding, Emma von Witting, Tianqi Xu, Anzhelika Vorobyeva, Maryam Oroujeni, Anna Orlova, Sophia Hober, Torbjörn Gräslund, Vladimir Tolmachev
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-11-01
Series:	Pharmaceutics
Assuntos:	ADAPT human epidermal growth factor receptor 2 HER2 DM1 albumin binding domain
Acceso en liña:	https://www.mdpi.com/1999-4923/13/11/1847
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