8-OxoG-Dependent Regulation of Global Protein Responses Leads to Mutagenesis and Stress Survival in <i>Bacillus subtilis</i>

The guanine oxidized (GO) system of <i>Bacillus subtilis</i>, composed of the YtkD (MutT), MutM and MutY proteins, counteracts the cytotoxic and genotoxic effects of the oxidized nucleobase 8-OxoG. Here, we report that in growing <i>B. subtilis</i> cells, the genetic inactivation of GO system potent...

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Hauptverfasser:	Lissett E. Martínez, Gerardo Gómez, Norma Ramírez, Bernardo Franco, Eduardo A. Robleto, Mario Pedraza-Reyes
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-03-01
Schriftenreihe:	Antioxidants
Schlagworte:	<i>Bacillus subtilis</i> 8-oxoG GO system mutagenesis oxidative stress
Online-Zugang:	https://www.mdpi.com/2076-3921/13/3/332
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