The interaction of fibrinolysis and the complement system in patients with acute pulmonary embolism, treated with ultrasound-assisted catheter-directed thrombolysis

Abstract Ultrasound-assisted catheter-directed thrombolysis (USAT) with recombinant tissue-type plasminogen activator (rt-PA) is widely used as a reperfusion approach for acute pulmonary embolism (PE). The fibrinolytic effector protease plasmin is known to be a potent activator of the complement sys...

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Auteurs principaux:	Dominik F. Draxler, Christopher D. Barrett, Justine Brodard, Elizabeth R. Maginot, Konstantina Chalkou, Heidi Ho, Charithani B. Keragala, Dik Heg, Johanna A. Kremer Hovinga, Ernest E. Moore, Robert L. Medcalf, Anne Angelillo-Scherrer, Stefan Stortecky
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2026-01-01
Collection:	Thrombosis Journal
Sujets:	Pulmonary embolism Catheter-directed thrombolysis Fibrinolysis Fibrinolytic potential Fibrinolytic capacity Inflammation
Accès en ligne:	https://doi.org/10.1186/s12959-026-00830-3
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