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Intranasal M2SR and BM2SR Vaccine Viruses Do Not Shed or Transmit in Ferrets

Background/Objectives: Live influenza vaccines are considered to stimulate better overall immune responses but are associated with safety concerns regarding shedding and the potential for transmission or reassortment with wild-type influenza viruses. Intranasal M2SR and BM2SR (M2- and BM2-deficient...

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Autori principali: Yasuko Hatta, Lindsay Hill-Batorski, Michael J. Moser, David Marshall, David A. Boltz, Landon Westfall, Renee Herber, Sally Sarawar, Pamuk Bilsel
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2024-10-01
Serie:Vaccines
Soggetti:
M2-deficient
shedding
live
influenza
M2
BM2
Accesso online:https://www.mdpi.com/2076-393X/12/11/1228
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