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Neutralization of Human Cytomegalovirus Entry into Fibroblasts and Epithelial Cells

Human cytomegalovirus (HCMV) is a leading cause of permanent birth defects, highlighting the need to develop an HCMV vaccine candidate. However, HCMV vaccine development is complicated by the varying capacity of neutralizing antibodies (NAb) to interfere in vitro with the HCMV entry routes mediating...

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Principais autores: Felix Wussow, Flavia Chiuppesi, Heidi Contreras, Don J. Diamond
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2017-10-01
Serier:Vaccines
Fag:
cytomegalovirus
neutralizing antibody
fibroblasts
epithelial cells
vaccine
glycoprotein complex
pentamer
Online adgang:https://www.mdpi.com/2076-393X/5/4/39
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