High cumulative glucocorticoid dose is associated with increased levels of inflammation-related mediators in active rheumatoid arthritis

IntroductionGlucocorticoids (GCs) are widely used as a treatment for rheumatoid arthritis (RA), leading to high cumulative doses in long-term treated patients. The impact of a high cumulative GC dose on the systemic inflammatory response in RA remains poorly understood.MethodsWe investigated long-tr...

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Hlavní autoři:	Anna Petrackova, Pavel Horak, Jakub Savara, Martina Skacelova, Eva Kriegova
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-12-01
Edice:	Frontiers in Immunology
Témata:	autoimmune diseases adverse effects of glucocorticoids systemic inflammation cytokine profile long-treated patients disease activity
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1505615/full
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