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Recombinant Antibodies against Mycolactone

In the past, it has proved challenging to generate antibodies against mycolactone, the primary lipidic toxin A of <i>Mycobacterium ulcerans</i> causing Buruli ulcer, due to its immunosuppressive properties. Here we show that in vitro display, comprising both phage and yeast display, can be used to s...

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Principais autores: Leslie Naranjo, Fortunato Ferrara, Nicolas Blanchard, Caroline Demangel, Sara D’Angelo, M. Frank Erasmus, Andre A. Teixeira, Andrew R.M. Bradbury
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-06-01
Serier:Toxins
Fag:
mycolactone
Buruli ulcer
recombinant antibody
phage display
yeast display
single chain Fv
Online adgang:https://www.mdpi.com/2072-6651/11/6/346
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