Steady-state memory-phenotype conventional CD4+ T cells exacerbate autoimmune neuroinflammation in a bystander manner via the Bhlhe40/GM-CSF axis

Abstract Memory-phenotype (MP) CD4+ T cells are a substantial population of conventional T cells that exist in steady-state mice, yet their immunological roles in autoimmune disease remain unclear. In this work, we unveil a unique phenotype of MP CD4+ T cells determined by analyzing single-cell tran...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Min-Ji Cho, Hong-Gyun Lee, Jae-Won Yoon, Gil-Ran Kim, Ja-Hyun Koo, Reshma Taneja, Brian T. Edelson, You Jeong Lee, Je-Min Choi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2023-05-01
coleção:	Experimental and Molecular Medicine
Acesso em linha:	https://doi.org/10.1038/s12276-023-00995-1
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!