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Tryptophanase Expressed by <i>Salmonella</i> Halts Breast Cancer Cell Growth In Vitro and Inhibits Production of Immunosuppressive Kynurenine

Tryptophan is an essential amino acid required for tumor cell growth and is also the precursor to kynurenine, an immunosuppressive molecule that plays a role in limiting anticancer immunity. Tryptophanase (TNase) is an enzyme expressed by different bacterial species that converts tryptophan into ind...

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Bibliografische Detailangaben
Hauptverfasser: Eljoie Anice Cada Hababag, Allea Cauilan, David Quintero, David Bermudes
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-05-01
Schriftenreihe:Microorganisms
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Online-Zugang:https://www.mdpi.com/2076-2607/11/5/1355
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