Multi-payload antibody-drug conjugates for photothermal dynamic and chemotherapy of HER2-positive breast cancer

HER2-positive breast cancer is highly aggressive and has a poor prognosis in clinical treatment primarily due to the overexpression of HER2 protein. Trastuzumab can significantly improve the therapeutic outcome for HER2-positive breast cancer, but 70% of patients develop drug resistance. Trastuzumab...

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Hauptverfasser:	Yuqi Zhang, Yongxiang Bai, Xingxiang Ren, Yurong Fan, Zhengzhong Lv, Qingfei Song, Xiaoyan Wang, Haibin Shi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-08-01
Schriftenreihe:	Materials Today Bio
Schlagworte:	Antibody-drug conjugates Photothermal-thermodynamic therapy (PTDT) Chemotherapy HER2-Positive breast cancer
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2590006426006009
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