Neutralization and spike stability of JN.1-derived LB.1, KP.2.3, KP.3, and KP.3.1.1 subvariants

ABSTRACT During the summer of 2024, coronavirus disease 2019 (COVID-19) cases surged globally, driven by variants derived from JN.1 subvariants of severe acute respiratory syndrome coronavirus 2 that feature new mutations, particularly in the N-terminal domain (NTD) of the spike protein. In this stu...

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Principais autores:	Pei Li, Julia N. Faraone, Cheng Chih Hsu, Michelle Chamblee, Yajie Liu, Yi-Min Zheng, Yan Xu, Claire Carlin, Jeffrey C. Horowitz, Rama K. Mallampalli, Linda J. Saif, Eugene M. Oltz, Daniel Jones, Jianrong Li, Richard J. Gumina, Joseph S. Bednash, Kai Xu, Shan-Lu Liu
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2025-05-01
Series:	mBio
Assuntos:	SARS-CoV-2 JN.1 subvariants DelS31 mutation spike protein stability immune evasion cell-cell fusion
Acceso en liña:	https://journals.asm.org/doi/10.1128/mbio.00464-25
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