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T-cell repertoire correlates with cytokine imbalance in multiple sclerosis patients

IndroductionMultiple sclerosis (MS) is mediated by innate and adaptive immune response deviation involving immune cells and cytokines. Here, we investigated whether combined cytokine profiling and T-cell receptor (TCR) repertoire analysis can better display the complex landscape of MS-driving immune...

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Principais autores: Lisa Weidner, Rodolphe Poupardin, Tobias Zrzavy, Sandra Laner-Plamberger, Georg Gratz, Tanja Eichhorn, Viktoria Weber, Paulus S. Rommer, Christof Jungbauer, Dirk Strunk
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-07-01
coleção:Frontiers in Immunology
Assuntos:
neuroscience
multiple sclerosis
T cell repertoire
cytokine imbalance
bioinformatics
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1604452/full
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