Deregulated Nras expression in knock-in animals harboring a gammaretroviral long terminal repeat at the Nras/Csde1 locus.

To investigate mechanisms and phenotypic effects of insertional mutagenesis by gammaretroviruses, we have developed mouse lines containing a single Akv 1-99 long terminal repeat (LTR) and a floxed PGK/Tn5 neomycin cassette at the Nras proto-oncogene at positions previously identified as viral integr...

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Principais autores:	Borja Ballarín-González, Louise Berkhoudt Lassen, Randi Jessen, Annette Füchtbauer, Ernst-Martin Füchtbauer, Finn Skou Pedersen
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2013-01-01
叢編:	PLoS ONE
在線閱讀:	http://europepmc.org/articles/PMC3572152?pdf=render
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