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DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism

Abstract Gastric cancer (GC) is a prevalent malignant tumor of the digestive system that is often diagnosed at advanced stages owing to inconspicuous early symptoms and a lack of specific examination methods. Effective treatment of advanced stages remains challenging, emphasizing the need for new th...

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Principais autores: Xinrong Wu, Yifan Li, Weiwei Wang, Jiale Xu, Bei Zhao, Wenqi Sun, Dan Ge, Longying Xiong, Xiaotan Dou, Xiaoping Zou, Lei Wang, Min Chen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-01-01
Serier:Scientific Reports
Fag:
PI3K/AKT/mTOR pathway
DRAM1
Gastric cancer
Energy metabolism
Atorvastatin
Online adgang:https://doi.org/10.1038/s41598-025-87389-7
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