Severe developmental B lymphopoietic defects in Foxp3-deficient mice are refractory to adoptive regulatory T cell therapy

The role of Foxp3-expressing regulatory T (Treg) cells in tolerance and autoimmunity is well established. However, although of considerable clinical interest, the role of Treg cells in the regulation of hematopoietic homeostasis remains poorly understood. Thus, we analysed B and T lymphopoiesis in t...

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Detalhes bibliográficos

Principais autores:	Julia eRiewaldt, Sandra eDüber, Marie eBoernert, Marcin eDembinski, Siggi eWeiss, Annette I Garbe, Karsten eKretschmer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2012-06-01
coleção:	Frontiers in Immunology
Assuntos:	Autoimmunity Lymphopoiesis B cell Regulatory T Cell Foxp3 Scurfy
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00141/full
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