Preparation and optimization of various parameters of enteric coated pellets using the Taguchi L9 orthogonal array design and their characterization
Duloxetine hydrochloride enteric coated pellets were formulated using fluidized bed. Three separate layers, the drug layer, the barrier layer, and the enteric layer, were coated onto the inert core pellets. The pellets were optimized with the acid resistance and drug release in simulated intestinal...
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| Principais autores: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2011-06-01
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| Serier: | Acta Pharmaceutica Sinica B |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S2211383511000062 |
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