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Properdin and Factor H: Opposing players on the alternative complement pathway see-saw

Properdin and factor H are two key regulatory proteins having opposite functions in the alternative complement pathway. Properdin up-regulates the alternative pathway by stabilising the C3bBb complex, whereas factor H down-regulates the pathway by promoting proteolytic degradation of C3b. While fact...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Lubna eKouser, Munirah eAbdul-Aziz, Annapurna eNayak, Cordula M Stover, Robert B Sim, Uday eKishore
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2013-04-01
Rangatū:Frontiers in Immunology
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00093/full
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