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microRNA-122 inhibits hepatic stellate cell proliferation and activation in vitro and represses carbon tetrachloride-induced liver cirrhosis in mice

Objective: This study aimed to determine the roles of microRNA (miR)-122 in the activation of hepatic stellate cells (HSCs) and liver cirrhosis. Methods: Rat primary HSCs were incubated with transforming growth factor-beta (TGF-β), during which miR-122 and EphB2 expression was measured. miR-122 mimi...

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Principais autores: Jing Ma, Qiqian Zhao, Mengxuan Chen, Weihang Wang, Bo He, Yongfang Jiang, Yi Li
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2022-07-01
Serija:Annals of Hepatology
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Online dostop:http://www.sciencedirect.com/science/article/pii/S1665268122000424
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