Dexmedetomidine vs. midazolam-fentanyl for intraoperative analgesia and sedation: a systematic review and meta analysis

BackgroundOngoing research aims to identify the most effective sedative for procedural sedation. This meta-analysis compares dexmedetomidine with midazolam-fentanyl in surgical patients.MethodsWe conducted a search through MEDLINE, EMBASE and CENTERAL to find randomized controlled trials (RCTs) comp...

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Egile Nagusiak:	Hashim Talib Hashim, Mostafa A. Khalifa, Aya Ahmed Shimal, Marafi Jammaa Ahmed, Mohamed H. Elbadawi, Khadeeja Ali Hamzah, Abdulhadi M. A. Mahgoub, Alaa R. AL-Ihribat, Salem Waleed Salem Mohamed, Fathima Raahima Riyas Mohamed, Elian Khalafalla, Amna Kamil, Anzah Imtiaz Wagga, Ahmed Mohamed Shahin, Abdelrhman H. Mohammed
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2026-03-01
Saila:	Frontiers in Pain Research
Gaiak:	analgesia dexmedetomidine midazolam midazolam-fentanyl sedation
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fpain.2026.1664460/full
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