Study of vascular endothelial dysfunction in children with beta-thalassemia major before and after quercetin therapy

Abstract Background Beta-thalassemia stands as an autosomal recessive disorder that occurs as a result of a defect in the beta-globin chain synthesis of hemoglobin. Oxidative stress has a crucial role in the β-thalassemia pathophysiology. It occurs due to erythroid expansion along with ineffective e...

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Autors principals:	Fatma Al Zahraa Sherai, Maaly Mabrouk, Ibrahim Badraia, Adel Hagag, Eman Elaskary
Format:	Artigo
Idioma:	Inglês
Publicat:	SpringerOpen 2025-02-01
Col·lecció:	Egyptian Pediatric Association Gazette
Matèries:	Thalassemia Iron overload Oxidative stress Quercetin ROS Thrombomodulin
Accés en línia:	https://doi.org/10.1186/s43054-025-00347-w
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