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Dupilumab in the Treatment of Severe Uncontrolled Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) and Comorbid Asthma—A Multidisciplinary Monocentric Real-Life Study

<b>Background:</b> Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma are mutually correlated with Type-2 inflammation. Dupilumab is effective in uncontrolled and relapsing CRSwNP. However, the precise characterization of Type-2 inflammation and the impact of previous surgery on clinical o...

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Principais autores: Gian Luca Fadda, Chiara Rustichelli, Simone Soccal, Simone Moglio, Alessandro Serrone, Francesca Bertolini, Vitina Carriero, Stefano Pizzimenti, Stefano Levra, Giovanni Cavallo, Fabio Luigi Massimo Ricciardolo, Giuseppe Guida
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-02-01
Serier:Biomedicines
Fag:
nasal polyps
chronic rhinosinusitis
asthma
type-2 inflammation
biologic treatment
dupilumab
Online adgang:https://www.mdpi.com/2227-9059/13/2/501
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