Senolytics and Senomorphics Targeting p38MAPK/NF-κB Pathway Protect Endothelial Cells from Oxidative Stress-Mediated Premature Senescence

Oxidative stress is a prominent causal factor in the premature senescence of microvascular endothelial cells and the ensuing blood–brain barrier (BBB) dysfunction. Through the exposure of an in vitro model of human BBB, composed of brain microvascular endothelial cells (BMECs), astrocytes, and peric...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Jingyuan Ya, Ulvi Bayraktutan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2024-07-01
Edice:	Cells
Témata:	endothelial cell senescence p38MAPK NF-κB blood–brain barrier senotherapeutic
On-line přístup:	https://www.mdpi.com/2073-4409/13/15/1292
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!