Development of Thermoresponsive-Gel-Matrix-Embedded Amoxicillin Trihydrate-Loaded Bovine Serum Albumin Nanoparticles for Local Intranasal Therapy

A high dose of amoxicillin is recommended as the first-line therapy for acute bacterial rhinosinusitis (ABR). However, oral administration of amoxicillin is connected to many adverse reactions coupled with moderate bioavailability (~60%). Therefore, this study aimed to develop a topical nasal prepar...

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Detalhes bibliográficos

Principais autores:	Sandra Aulia Mardikasari, Mária Budai-Szűcs, László Orosz, Katalin Burián, Ildikó Csóka, Gábor Katona
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-11-01
coleção:	Gels
Assuntos:	amoxicillin BSA Poloxamer 407 in situ gelling system intranasal delivery rhinosinusitis
Acesso em linha:	https://www.mdpi.com/2310-2861/8/11/750
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