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Mismatch Repair Deficiency and Microsatellite Instability in Triple-Negative Breast Cancer: A Retrospective Study of 440 Patients

PurposeTo investigate the status of mismatch repair (MMR) and microsatellite instability (MSI) in triple-negative breast cancer (TNBC) and to examine correlations between MMR/MSI status and clinicopathological parameters.MethodsWe retrospectively collected tissue samples from 440 patients with TNBC...

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Principais autores: Xin-yu Ren, Yu Song, Jing Wang, Long-yun Chen, Jun-yi Pang, Liang-rui Zhou, Song-jie Shen, Xi Cao, Yu-xin Wang, Miao-miao Shao, Zhi-yong Liang, Qiang Sun, Huan-wen Wu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-03-01
Serier:Frontiers in Oncology
Fag:
triple-negative breast cancer (TNBC)
mismatch repair (MMR) deficiency
microsatellite instability
prognosis
mismatch repair proficiency
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2021.570623/full
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