AIM2 Engages Active but Unprocessed Caspase-1 to Induce Noncanonical Activation of the NLRP3 Inflammasome

Inflammasomes are multimeric protein complexes that initiate inflammatory cascades. Their activation is a hallmark of many infectious or inflammatory diseases. Their composition and activity are specified by proinflammatory stimuli. For example, the NLRP3 inflammasome is activated in response to cel...

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Egile Nagusiak:	Larissa D. Cunha, Alexandre L.N. Silva, Juliana M. Ribeiro, Danielle P.A. Mascarenhas, Gustavo F.S. Quirino, Leonardo L. Santos, Richard A. Flavell, Dario S. Zamboni
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2017-07-01
Saila:	Cell Reports
Gaiak:	AIM2 caspase-1 inflammasomes Legionella pneumophila NLRP3
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2211124717309348
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