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Large-scale death of retinal astrocytes during normal development is non-apoptotic and implemented by microglia.

Naturally occurring cell death is a fundamental developmental mechanism for regulating cell numbers and sculpting developing organs. This is particularly true in the nervous system, where large numbers of neurons and oligodendrocytes are eliminated via apoptosis during normal development. Given the...

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Principais autores: Vanessa M Puñal, Caitlin E Paisley, Federica S Brecha, Monica A Lee, Robin M Perelli, Jingjing Wang, Emily G O'Koren, Caroline R Ackley, Daniel R Saban, Benjamin E Reese, Jeremy N Kay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2019-10-01
coleção:PLoS Biology
Acesso em linha:https://doi.org/10.1371/journal.pbio.3000492
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