A validated liquid chromatography‐tandem mass spectroscopy method for the quantification of tolinapant in human plasma
Abstract Tolinapant (ASTX660), a pan‐selective inhibitor of apoptosis protein antagonist with dual cIAP/XIAP activity, was identified as a clinical candidate in preclinical efficacy, pharmacokinetic and safety studies. In order to assess tolinapant in first‐in‐human Phase I/II clinical trials, a val...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley-VCH
2022-06-01
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| Serie: | Analytical Science Advances |
| Accesso online: | https://doi.org/10.1002/ansa.202200009 |
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