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Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domain

<p>Abstract</p> <p>Background</p> <p>Scaffold proteins have an important role in the regulation of signal propagation. These proteins do not possess any enzymatic activity but can contribute to the formation of multiprotein complexes. Although scaffold proteins are present in all cell types, the ner...

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Principais autores: Pesti Szabolcs, Balázs Annamária, Udupa Roopesh, Szabó Beáta, Fekete Anna, Bőgel Gábor, Buday László
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2012-11-01
Serier:Cell Communication and Signaling
Fag:
EphB1 receptor tyrosine kinase
Nck
Caskin1
SH3 domain
CD spectrum
Online adgang:http://www.biosignaling.com/content/10/1/36
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