Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction

Retinal pigment epithelial (RPE) cells maintain the health and functional integrity of both photoreceptors and the choroidal vasculature. Loss of RPE differentiation has long been known to play a critical role in numerous retinal diseases, including inherited rod-cone degenerations, inherited macula...

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Autors principals:	Mi Zhou, Jasmine S. Geathers, Stephanie L. Grillo, Sarah R. Weber, Weiwei Wang, Yuanjun Zhao, Jeffrey M. Sundstrom
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2020-06-01
Col·lecció:	Frontiers in Cell and Developmental Biology
Matèries:	RPE dedifferentiation RPE dysfunction EMT UPR retinal degeneration
Accés en línia:	https://www.frontiersin.org/article/10.3389/fcell.2020.00501/full
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