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Quantitative Analysis of Survivin Protein Expression and Its Therapeutic Depletion by an Antisense Oligonucleotide in Human Lung Tumors

RNA-directed antisense and interference therapeutics are a promising treatment option for cancer. The demonstration of depletion of target proteins within human tumors in vivo using validated methodology will be a key to the application of this technology. Here, we present a flow cytometric-based ap...

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Principais autores: Anna L Olsen, Joanne M Davies, Louise Medley, David Breen, Denis C Talbot, Peter J McHugh
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2012-01-01
Serija:Molecular Therapy: Nucleic Acids
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2162253116300841
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