HMGB1 and its membrane receptors as therapeutic targets in an intravesical substance P-induced bladder pain syndrome mouse model

HMGB1, a nuclear protein, once released to the extracellular space, promotes somatic and visceral pain signals. We thus analyzed the role of HMGB1 in an intravesical substance P-induced bladder pain syndrome (BPS) mouse model. Intravesical administration of substance P caused referred hyperalgesia/a...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yuhei Irie, Maho Tsubota, Mariko Maeda, Shiori Hiramoto, Fumiko Sekiguchi, Hiroyasu Ishikura, Hidenori Wake, Masahiro Nishibori, Atsufumi Kawabata
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2020-06-01
Цуврал:	Journal of Pharmacological Sciences
Нөхцлүүд:	HMGB1 Substance P Bladder pain syndrome
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S1347861320300293
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!