Untranslated regions (UTRs) are a potential novel source of neoantigens for personalised immunotherapy

BackgroundNeoantigens, mutated tumour-specific antigens, are key targets of anti-tumour immunity during checkpoint inhibitor (CPI) treatment. Their identification is fundamental to designing neoantigen-directed therapy. Non-canonical neoantigens arising from the untranslated regions (UTR) of the gen...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Christopher C. T. Sng, Ashwin Adrian Kallor, Benjamin S. Simpson, Georges Bedran, Javier Alfaro, Kevin Litchfield
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2024-03-01
Sarja:	Frontiers in Immunology
Aiheet:	UTR untranslated region neoantigen checkpoint inhibitor personalised vaccine PrimeCUTR
Linkit:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1347542/full
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