QR-Code

Role of FLCN Phosphorylation in Insulin‐Mediated mTORC1 Activation and Tumorigenesis

Abstract The amino acid‐stimulated Rag GTPase pathway is one of the main pathways that regulate mechanistic target of rapamycin complex 1 (mTORC1) activation and function, but little is known about the effects of growth factors on Rag GTPase‐mediated mTORC1 activation. Here, a highly conserved insul...

Ausführliche Beschreibung

Gespeichert in:
Bibliografische Detailangaben
Hauptverfasser: Guoyan Wang, Lei Chen, Xinjian Lei, Senlin Qin, Huijun Geng, Yining Zheng, Chao Xia, Junhu Yao, Tong Meng, Lu Deng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2023-06-01
Schriftenreihe:Advanced Science
Schlagworte:
Online-Zugang:https://doi.org/10.1002/advs.202206826
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!