TRANSCRIPTOMIC PROFILING SUGGESTS DYSREGULATED ACTIVATION OF B AND T LYMPHOCYTES IN PHILADELPHIA-NEGATIVE MYELOPROLIFERATIVE NEOPLASMS
Introduction and aims: Myeloproliferative neoplasms (MPN) are clonal hematological diseases characterized by exacerbated proliferation of cells belonging to the myeloid lineage. Gain of function driver mutations in the Janus Kinase 2 (JAK2), calreticulin (CALR), and thrombopoietin receptor (MPL) gen...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2024-10-01
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| Серии: | Hematology, Transfusion and Cell Therapy |
| Online-ссылка: | http://www.sciencedirect.com/science/article/pii/S2531137924011209 |
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