Prenatal diagnosis of Down syndrome combined with transient abnormal myelopoiesis in foetuses with a GATA1 gene variant: two case reports

Abstract Background Down syndrome myeloid hyperplasia includes transient abnormal myelopoiesis (TAM) and the myeloid leukemia associated with Down syndrome (ML-DS). The mutation of GATA1 gene is essential in the development of Down syndrome combined with TAM or ML-DS. Some patients with TAM are asym...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Hui Tang, Jingjing Hu, Ling Liu, Lijuan Lv, Jian Lu, Jiexia Yang, Jiaqi Lu, Zhenhui Chen, Chaoxiang Yang, Dan Chen, Jintao Fu, Jing Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-10-01
coleção:	Molecular Cytogenetics
Assuntos:	Transient abnormal myelopoiesis Down syndrome Trisomy 21 GATA1 Prenatal diagnosis
Acesso em linha:	https://doi.org/10.1186/s13039-023-00658-w
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!