Identification of a conserved subset of cold tumors responsive to immune checkpoint blockade

Background The efficacy of immune checkpoint blockade (ICB) depends on restoring immune recognition of cancer cells that have evaded immune surveillance. Transforming growth factor-beta (TGFβ) is associated with immune-poor, so-called cold tumors whereas loss of its signaling promotes DNA misrepair...

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Detalhes bibliográficos

Principais autores:	Mary Helen Barcellos-Hoff, Alexis Combes, Matthew Spitzer, Kobe Yuen, Jade Moore, Jim Gkantalis, Ines Guix, William Chou, Ann A Lazar
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMJ Publishing Group 2025-03-01
coleção:	Journal for ImmunoTherapy of Cancer
Acesso em linha:	https://jitc.bmj.com/content/13/3/e010528.full
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