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Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1

Abstract Background Itch is an unpleasant sensation that can be debilitating, especially if it is chronic and of non-histaminergic origin, as treatment options are limited. Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor that also has the ability to induce a burning, non-histaminergic pru...

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Бібліографічні деталі
Автори: Elín I. Magnúsdóttir, Mirjana Grujic, Jessica Bergman, Gunnar Pejler, Malin C. Lagerström
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2020-04-01
Серія:Journal of Neuroinflammation
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Онлайн доступ:http://link.springer.com/article/10.1186/s12974-020-01795-4
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