The E3 ligase c-Cbl modulates microglial phenotypes and contributes to Parkinson’s disease pathology
Abstract Microglial activation, particularly the polarization between classical (M1 phenotype) and alternative (M2 phenotype) states, plays pivotal roles in the immune pathogenesis of Parkinson’s disease (PD), with the M1 phenotype exerting neurotoxic effects and the M2 phenotype conferring neuropro...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2025-04-01
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| Edice: | Cell Death Discovery |
| On-line přístup: | https://doi.org/10.1038/s41420-025-02482-0 |
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