Disrupted mitochondrial morphology and function exacerbate inflammation in elderly-onset ulcerative colitis

Abstract Background The characteristics of ulcerative colitis (UC) in the elderly are quite different from the young population. Mitochondrial injury is a key mechanism regulating both aging and inflammation. This study aims to reveal the role of mitochondrial damage in the pathogenesis of adult- an...

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Autores principales:	Mengmeng Zhang, Hong Lv, Xiaoyin Bai, Gechong Ruan, Qing Li, Kai Lin, Hong Yang, Jiaming Qian
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-01-01
Colección:	Immunity & Ageing
Materias:	Ulcerative colitis Elderly Mitochondrial damage Inflammatory response Immune infiltration
Acceso en línea:	https://doi.org/10.1186/s12979-024-00494-5
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